Using Routine Inflammatory and Metabolic Blood Tests (Bedside Included) to Predict Brain Injury in Children After Minor Head Trauma

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 18
SponsorIuliu Hatieganu University of Medicine and Pharmacy

About this trial

Traumatic brain injury (TBI) poses significant strains on the paediatric population, for which the possible side effects of diagnostic imagistics could induce life-altering conditions. Routine inflammatory and metabolic biomarkers (complete blood count, C reactive protein, glucose) are frequently sampled in the paediatric patients admited within emergency departments, including the low-resource settings. This study aims to retrospectively document whether such routine blood biomarkers could predict a positive head CT scan and subsequently contribute to a prediction score, ment to enable more accurate decision on which minor TBI paediatric patients should be submitted to diagnotic imagistics.

Eligibility criteria

Qualifiers

Mild TBI will be defined as GCS 14-15 or A (AVPU) upon admission

Patients underwent head CT

Routine blood biomarkers have been collected (complete blood count - CBC, biochemistry and/or (arterial) venos blood gases - (A)VBG).

Disqualifiers

Patients with moderate (GCS 13-9 or V) or severe (GCS 8-3 or P,U) head trauma

Patients with associated trauma (limb/rib/pelvic fractures, organ injuries).

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

800 Participants
are grouped into 1 trial group

Sponsors and collaborators

Iuliu Hatieganu University of Medicine and Pharmacy

Lead sponsor

Children's Emergency Clinical Hospital Cluj-Napoca

Collaborator