Uterine Microbiome in Recurrent Pregnancy Loss
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-38
SponsorMỹ Đức Hospital
About this trial
The female genital tract microbiome may reflect female reproductive health and may be related to pregnancy outcomes. Disturbances in this microbiome may be associated with adverse reproductive outcomes. The investigators hypothesize that the endometrial and vaginal microbiome composition in women with a history of recurrent pregnancy loss are different, compared with those in normal fertile women.
Eligibility criteria
Qualifiers
Recurrent pregnancy loss patients
18-38 years old
Having a regular menstrual cycle, from 25 to 35 days
Having ≥ 2 recurrent pregnancy loss and
Disqualifiers
Irregular menstrual cycle
Having uterine abnormalities (e.g., adenomyosis, intrauterine adhesions, unicornuate/ bicornuate/ arcuate uterus; unremoved hydrosalpinx, endometrial polyp, submucosal fibroid)
Using intrauterine device within the last 3 months
Using antibiotic/vaginal pessary/contraceptive pills within 2 weeks
Trial design
Treatments tested in this trial
- Vaginal swab and endometrial biopsy
Treatment groups
100 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov