Utility of PCD Diagnostics to Improve Clinical Care
ConditionPrimary Ciliary Dyskinesia
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age2+
SponsorConnecticut Children's Medical Center
About this trial
This cross-sectional and longitudinal observational study is to gather data on the utility of tests that are used to make a diagnosis of primary ciliary dyskinesia (PCD). There is new testing available, called nasal nitric oxide testing, that non-invasively measures nitric oxide levels in the sinus cavity. Individuals with PCD characteristically have low levels, but this testing does not have extensive data from everyday clinical practice. The objective of this proposal is to improve the diagnostic approach to children and adults with clinical concerns for primary ciliary dyskinesia (PCD).
Eligibility criteria
Qualifiers
Age ≥ 2 years of age
Neonatal respiratory distress
Chronic nasal congestion/runny nose
Chronic cough
Disqualifiers
Recent history of sinus surgery or bloody nose in the past week
Age < 2 years of age
Inability to tolerate probe in nose
Sinusitis or other respiratory exacerbation currently being treated with antibiotics
Trial design
Treatments tested in this trial
- Nasal Nitric Oxide testing
Treatment groups
50 Participants
are divided into 1 treatment groupSponsors and collaborators
Connecticut Children's Medical Center
Lead sponsor
UConn Health
Collaborator
Source ClinicalTrials.gov