About this trial
This is a pilot project to explore the utility of PET-MRI in the post-treatment surveillance of high-grade gliomas or medulloblastomas in children in our institution.
Eligibility criteria
Qualifiers
Have a presumptive or histologically confirmed diagnosis of a malignant brain tumour requiring treatment
Diagnostic uncertainty about tumour recurrence post-treatment based on conventional MR imaging in the opinion of the MDT
Have a life expectancy of at least three months
Able to comply with an MRI scan without a general anaesthetic
Disqualifiers
Unable to comply with an MRI scan without a general anaesthetic
Diabetes or other causes of hyperglycaemia
Pregnancy
Patient body habitus above scanner dimensions
Trial design
Treatments tested in this trial
- PET-MRI
Treatment groups
Sponsors and collaborators
Sheffield Children's NHS Foundation Trust
Lead sponsor
GE Healthcare
Collaborator
University of Sheffield
Collaborator