About this trial
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, frequently presents with musculoskeletal extraintestinal manifestations (EIMs), such as arthritis and enthesitis, affecting up to 50% of patients. These can be subclinical and are often underestimated by physical examination alone. Musculoskeletal ultrasound (MSK-US) is a sensitive, non-invasive tool for detecting both clinical and subclinical inflammation. Despite its benefits, there is no standardized MSK-US protocol specifically for IBD patients. This study aims to develop a structured MSK-US assessment protocol, evaluate its effectiveness in detecting musculoskeletal involvement, and investigate its relationship with IBD disease activity.
Eligibility criteria
Qualifiers
patients diagnosed with inflammatory bowel disease (Crohn's disease or ulcerative colitis)
Patients without a definite diagnosis of inflammatory arthritis, to focus on subclinical musculoskeletal involvement.
Disqualifiers
Patients with a prior clinical diagnosis of inflammatory arthritis or other rheumatologic diseases.
Patients with complicated or severe comorbidities that may interfere with musculoskeletal evaluation or study participation (e.g., severe infections, malignancies).
Trial design
Treatments tested in this trial
- MSK Ultrasound with Doppler on joints, muscles & tendons