About this trial
Abdominal surgery, laparoscopic or open, is frequently performed at UPMC Shadyside hospital. One of the most frequent complications following abdominal surgery is a postoperative ileus. Although postoperative ileus may be the result of obstruction or leakage, in most cases postoperative ileus (POI) is the result of local irritation because of fluid overload, exogenous opioids, neurohormonal dysfunction, gastrointestinal stretch, local bleeding and inflammation. POI usually lasts between 2 to 7 days. In most cases, a nasogastric tube (NG tube) is used to relieve that gastric pressure until the resolution of the POI. The placement of a NG tube can lead to a local trauma, bleeding and pain. Pain represents a major complaint among those with POI, often contributing to prolonged hospital stays.
Eligibility criteria
Qualifiers
Adults (18 and older) undergoing laparoscopic or open colorectal surgery, or any major abdominal surgeries at UPMC Shadyside
Development of post-operative ileus
Anticipation of a nasogastric (ng) tube being placed
Disqualifiers
Pregnant subjects
Subjects who are unable to read, write, or speak English fluently
Subjects who have a developmental or neurological disorder and are not cognitively able to provide consent
Trial design
Treatments tested in this trial
- Vagal Nerve Stimulator
- Placebo Vagal Nerve Stimulator
Treatment groups
Sponsors and collaborators
Jacques E. Chelly
Lead sponsor
University of Pittsburgh
Sponsor institution