Vaginal Microbiome and HPV Pre-malignant and Cervical Dysplasia
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age25-70
SponsorHadassah Medical Organization
About this trial
In this study, the investigators will prospectively collect, analyze and integrate information regarding vaginal microbiome composition and HPV presence in women with cervical pathologies (high-grade CIN and CC) and controls, to construct a large dataset from patients with pre-cancerous cervical lesions and healthy women, to evaluate the personalized contribution of the vaginal microbiome to the CIN-CC sequence.
Eligibility criteria
Qualifiers
Age 25-70
Attended the clinic for a Pap smear or colposcopy
Disqualifiers
Patient does not approve sample collection
Usage of antibiotics in the month prior to clinic visit
Usage of any vaginal preparation or medication in the week prior to sample collection (anti-fungal, spermicides, lubricant etc.)
Menstruation
Trial design
Treatments tested in this trial
- Not listed
Trial groups
90 Participants
are grouped into 2 trial groupsSponsors and collaborators
Source ClinicalTrials.gov