Vaginal Microbiota and Post-cesarean SSI

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-40
SponsorAl-Azhar University

About this trial

The goal of this observational study is to investigate the relationship between vaginal microbiota composition and the development of post-cesarean section wound infection in women undergoing cesarean delivery. The main question it aims to answer is:

Is there a correlation between specific vaginal microbiota profiles and the incidence of post-cesarean section wound infection? Can specific bacterial taxa or diversity indices within the vaginal microbiota predict the risk of post-cesarean section wound infection?

Participants will:

Provide vaginal swab samples pre-operatively and post-operatively. Undergo standard post-cesarean section care and follow-up. Have wound assessment performed per standard of care, and have data collected regarding wound infection status.

Have demographic and clinical data collected, including but not limited to, antibiotic use, gestational age, and comorbidities.

Eligibility criteria

Qualifiers

Pregnant women undergoing elective or emergency cesarean section (CS).

Singleton pregnancy.

Cesarean section performed at ≥ 37 weeks of gestation.

Disqualifiers

Use of antibiotics within two weeks prior to delivery.

Known immunodeficiency.

Chronic infections.

Ruptured membranes for more than 18 hours.

Trial design

Treatments tested in this trial

  • Vaginal swab and culture

Treatment groups

160 Participants
are divided into 1 treatment group

Sponsors and collaborators