The goal of this observational study is to validate the Creyos online cognitive assessment platform in individuals with mild cognitive impairment, or remitted major depressive disorder. The main objectives of this research are:
1. To confirm the feasibility of administering the Creyos cognitive battery to older adults with Mild Cognitive Impairment MCI) or Major Depressive Disorder in remission (rMDD). 2. To determine whether the Creyos battery can detect changes in cognition that are predictive of changes on paper-and-pencil neuropsychological testing ("gold standard") over up to five years.
Participants will complete both in-person neuropsychological testing yearly as well as the Creyos online battery quarterly for up to 5 years, to allow us to compare performance on these two batteries over time.
Ability to read and communicate in English
Availability of a study partner who has regular contact with the participant
Lifetime DSM 5 diagnosis of schizophrenia, bipolar disorder, or OCD
DSM 5 diagnosis of alcohol or other substance use disorder within the past 12 months
High risk for suicide
Significant neurological conditions (e.g. stroke, seizure disorder, MS)
Centre for Addiction and Mental Health
Lead sponsor
Krembil Foundation
Collaborator