Validation and Simplification of the Retinol Isotope Dilution Technique in Burkinabe Schoolchildren

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age7-12
SponsorInstitut de Recherche en Sciences de la Sante, Burkina Faso

About this trial

Two cross-sectional, repeated-pass, community-based studies will be carried out during the school year. The first study will be conducted from November to December. This period corresponds to the end of the rainy season and the end of the mango season, which is one of the main sources of vitamin A in the Orodara region.

The second survey will be carried out 5 to 6 months (April-May of the following year) after data collection for the first study, corresponding to the mango season. The same schoolchildren recruited during the first phase of data collection (5 to 6 months earlier) will be the participants in the second study. The interest of this study is to use nuclear techniques to implement a strategy for the precise and accurate determination of Vitamin A status in order to reinforce existing Vitamin A interventions and policies.

Eligibility criteria

Qualifiers

School children aged 7-12 years

Child's guardian or parent is willing to provide informed consent

Child's family plans to remain resident in the study areas during the study period

Disqualifiers

Clinical evidence of vitamin A deficiency a mis en forme : Anglais (Royaume-Uni)a mis en forme : Anglais (États-Unis)a mis en forme : Anglais (États-Unis)a mis en forme : Anglais (États-Unis)

Severe malnutrition (weight-for age Z score (WAZ) or height-for-age Z score (HAZ) <-3 SD)

Serious illnesses including tuberculosis, symptomatic HIV infection

Child aged <6 years or >12 years

Trial design

Treatments tested in this trial

  • Retinol isotope dilution technique

Treatment groups

158 Participants
are divided into 3 treatment groups

Sponsors and collaborators

Institut de Recherche en Sciences de la Sante, Burkina Faso

Lead sponsor

International Atomic Energy Agency (IAEA)

Collaborator