Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorBrigham and Women's Hospital

About this trial

This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study satiety in healthy individuals.

TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held next to the scalp. In this study, the investigators will be stimulating the brain to learn more about the role of the cerebellum in satiety.

Eligibility criteria

Qualifiers

Healthy individuals aged 18 to 65

BMI of 20-35.0 kg/m2

Normal or corrected-to-normal vision

Good general health

Disqualifiers

Current and/or past medical conditions

Current and/or past eating disorder

On a restricted diet and/or taking weight loss medication(s)

History of bariatric surgery

Trial design

Treatments tested in this trial

  • Repetitive Transcranial Magnetic Stimulation (rTMS)
  • Sham repetitive Transcranial Magnetic Stimulation (rTMS)

Treatment groups

150 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Brigham and Women's Hospital

Lead sponsor

Mclean Hospital

Collaborator

Beth Israel Deaconess Medical Center

Collaborator