Validation of a Simplified Severity Score (Investigator Global Assessment: IGA) in Bullous Pemphigoid

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital, Rouen

About this trial

The aim of the study is to validate a global and simple score : IGA (Investigator Global Assessment) score for the evaluation of the extent and severity of the disease in patients with bullous pemphigoid

Eligibility criteria

Qualifiers

Consecutive adult patients aged ≥ 18 years

Newly diagnosed or relapsing BP

Clinical features suggestive of classic BP AND suggestive histological features AND deposition of IgG and/ or C3 deposits on the dermal epiderma junction, AND detection of circulating anti-epidermal antibodies labelling the epidermal side of salt-split skin

Patient having read and understood the information letter and not opposed to participation

Disqualifiers

Predominant or exclusive mucosal involvement leading to suspect the diagnosis of mucous membrane pemphigoid

Pemphigoid gestationis

Linear IgA dermatosis (predominant or exclusive IgA deposits on the DEJ)

Skin lesions suggesting the diagnosis of epidermolysis bullosa acquisita (skin fragility, atrophy, milia)

Trial design

Treatments tested in this trial

  • IGA score
  • BULLOUS PEMPHIGOID DISEASE AREA INDEX (BPDAI)

Treatment groups

150 Participants
are divided into 1 treatment group

Sponsors and collaborators