Validation of NAD+ Measurements for Human Clinical Studies
ConditionHealthy Adults
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-110
SponsorUniversity of Pennsylvania
About this trial
The purpose of this study is to determine nicotinamide adenine dinucleotide (NAD) levels in healthy adult subjects before and after supplementing with over-the counter nicotinamide riboside (NR) using magnetic resonance spectroscopy (MRS).
Eligibility criteria
Qualifiers
Male or female age18-35 years or 70 years or older, healthy
if female reproductive potential, use of highly effective contraception (at least 1 month prior to screening and during study participation).
No known sensitivity to NR
No use of niacin, blood thinners or chemotherapy agents
Disqualifiers
None
Trial design
Treatments tested in this trial
- Oral NR Supplementation
Treatment groups
48 Participants
are divided into 1 treatment groupSponsors and collaborators
University of Pennsylvania
Lead sponsor
National Institute on Aging (NIA)
Collaborator
Source ClinicalTrials.gov