Validation of Virtual Reality Tests for the Assessment of Patients With Age-related Macular Degeneration as Clinical Endpoints

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50+
SponsorStreetlab

About this trial

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in industrialized countries and affects tens of millions of people worldwide, with a rapidly increasing prevalence. It causes irreversible central vision loss and significant difficulties in daily activities, impairing patients' quality of life and independence. Conventional clinical assessments, which focus on visual acuity and retinal imaging, do not fully reflect the functional impact of the disease.

Virtual reality (VR) makes it possible to create immersive, controlled environments to accurately measure functional vision and simulate real-life situations. The study proposes to develop a standardized and reproducible functional test in virtual reality that can complement conventional examinations and support clinical and industrial research.

Eligibility criteria

Qualifiers

Age ≥ 50 years

Sufficient knowledge of the French language

Ability to give personal, express, free, and informed consent

Ability to comply with the requirements of the protocol

Disqualifiers

Pregnant women, women in labor, or breastfeeding women

Subjects undergoing drug treatments that may cause motor, visual, vestibular, or cognitive disorders (PSA, neuroleptics, etc.) or that could interfere with the study examinations

Any concomitant intraocular condition in the eye being studied (e.g., glaucoma or cataract)

Any retinal pathology that could cause retinal atrophy other than AMD (eliminate dystrophy, chronic CRSC, pachyatrophy, resorption of vitelliform material with atrophy, high myopia, etc.)

Trial design

Treatments tested in this trial

  • Object recognition and selection task

Treatment groups

60 Participants
are divided into 1 treatment group

Locations

This trial has no locations

Sponsors and collaborators

Streetlab

Lead sponsor

CIL - Centre Ophtalmologique d'Imagerie et de Laser

Collaborator

Fondation Ophtalmologique Adolphe de Rothschild

Collaborator