Vasopressor Agents in Pulmonary Hypertension Crisis

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorChina National Center for Cardiovascular Diseases

About this trial

Comparison of the efficacy and safety of three vasoactive agents-dopamine, norepinephrine, and epinephrine-in the treatment of patients with pulmonary hypertension crisis: prospective, randomised controlled trial monitored by haemodynamic monitoring

Eligibility criteria

Qualifiers

Age > 18 years old;

Signed informed consent form;

Confirmed diagnosis of arterial pulmonary hypertension (PAH) and/or chronic thromboembolic pulmonary hypertension (CTEPH);

Presenting with manifestations of pulmonary hypertensive crisis;

Disqualifiers

At SCAI stage D or stage E ;

Patients who only receive a diagnosis but no treatment in the hospital;

Uncontrolled hyperthyroidism;

Complicated with angle-closure glaucoma;

Trial design

Treatments tested in this trial

  • Norepinephrine
  • Dopamine
  • Epinephrine

Treatment groups

75 Participants
are divided into 3 treatment groups

Sponsors and collaborators

China National Center for Cardiovascular Diseases

Lead sponsor

Chinese Academy of Medical Sciences, Fuwai Hospital

Sponsor institution