VEDA Study (DHEA vs Estradiol)

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age40-90
SponsorUniversity of Arizona

About this trial

This study is being done to compare two vaginal treatments, vaginal estrogen and vaginal DHEA, that are used to treat vaginal and urinary symptoms related to menopause. These symptoms may include vaginal dryness, discomfort, painful intercourse, or urinary problems and can affect quality of life and sexual health. Women who choose to participate will be randomly assigned to use one of the two treatments for a set period of time. Participants will complete questionnaires about their symptoms and sexual health and have simple vaginal testing at the beginning and end of the study. The goal of this research is to better understand how these treatments affect vaginal health and sexual function so healthcare providers can make informed treatment decisions and improve care for postmenopausal women.

Eligibility criteria

Qualifiers

Peri- or post-menopausal status

Presence of any genitourinary or vaginal symptom (e.g., dryness, itching, discomfort, dyspareunia)

Willingness and ability to use vaginal therapy

Ability to provide informed consent

Disqualifiers

Use of systemic hormone therapy within the last 6 months

Gynecologic malignancy

Known allergy to study medications

Active vaginal infection at enrollment

Trial design

Treatments tested in this trial

  • DHEA ovals
  • Estradiol 0.01% Vag Cream

Treatment groups

324 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators