Venetoclax Resistance Landscape in Chronic Lymphocytic Leukemia

ConditionsChronic Lymphocytic Leukemia CLL Progressive Chronic Lymphocytic Leukemia Refractory Chronic Lymphocytic Leukemia Relapsed Chronic Lymphocytic Leukemia

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorUniversity Hospital, Clermont-Ferrand

About this trial

The purpose of this study is to collect medical informations and samples from refractory and/or relapsed chronic lymphocytic leukemia during or after venetoclax treatment, in order to evaluate the frequency of resistance mechanisms.

Eligibility criteria

Qualifiers

Age greater than or equal to 18 years old;

chronic lymphocytic leukemia diagnosis according to iwCLL criteria;

refractory and/or relapsed disease during or after venetoclax treatment;

tumor samples available.

Disqualifiers

None

Trial design

Treatments tested in this trial

Not listed

Trial groups

50 Participants

are grouped into 1 trial group

Sponsors and collaborators

University Hospital, Clermont-Ferrand

Lead sponsor

Source ClinicalTrials.gov