Ventilator-based Inspiratory Muscle Training for Patients With Respiratory Failure
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-55
SponsorCairo University
About this trial
This study will be conducted to compare the effectiveness of progressive inspiratory flow trigger sensitivity rising versus stepwise pressure support reduction as ventilator-based inspiratory muscle training methods on weaning and extubation success in mechanically ventilated patients with respiratory failure.
Eligibility criteria
Qualifiers
Acute respiratory failure patients in the ICU are receiving MV for 48 h or more in a controlled mode.
Their ages will range from 40 to 55 years old, and both sexes will be included.
Conscious and oriented patients with a Glasgow coma score ≥13 (≥9T).
Alertness score with a Richmond Agitation-Sedation Scale (RASS) will be from 0 to -1.
Disqualifiers
Persistent hemodynamic instability as life-threatening conditions or comorbidities interfere with and compromise weaning, like cardiac arrhythmia, pericardial effusion, congestive heart failure, or acute coronary syndrome.
Severe breathlessness when spontaneously breathing.
Any progressive neuromuscular disease, such as myopathy or neuropathy, that would interfere with responding to inspiratory muscle training due to inadequate training performance of the inspiratory muscle.
Spinal cord injury.
Trial design
Treatments tested in this trial
- adjustment of parameters on mechanical ventilation device
- routine plan of weaning and Conventional Chest Physiotherapy
Treatment groups
60 Participants
are divided into 3 treatment groupsLocations
1Map coordinates are unavailable for these locations. Locations are shown below instead.
kasr Al Ainy Hospital Status unavailable 11956, Cairo, Giza Governorate
Egypt
EgyptSponsors and collaborators
Source ClinicalTrials.gov