Ventilatory and Perfusion Abnormalities in Individuals With Post-Acute Sequelae of SARS-CoV-2 Infection
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-99
SponsorTufts Medical Center
About this trial
Prospective cohort study to evaluate the utility of quantitative CT analysis to assess ventilation and perfusion defects in patients with Post-acute Sequelae of SARS-CoV-2 (PASC) and functional limitations
Eligibility criteria
Qualifiers
Age ≥ 18
Self-reported or documented SARS-CoV-2 infection by RT-PCR or Antigen testing > 3 months ago or no previous history of SARS-CoV-2 infection (control group only)
Normal or mild abnormalities on baseline Pulmonary Function Tests (PFTs)
New or worsening symptoms of chronic fatigue, dyspnea or exercise intolerance after COVID-19 with otherwise unclear etiology (PASC group only)
Disqualifiers
SARS-CoV-2 infection by RT-PCR or Antigen testing within the last 3 months
Inability to provide consent or non-English speaking
Pregnancy
Any respiratory infection in last 4 weeks
Trial design
Treatments tested in this trial
- Computed Tomography of the Chest
Treatment groups
40 Participants
are divided into 3 treatment groupsSponsors and collaborators
Tufts Medical Center
Lead sponsor
4DMedical
Collaborator
Source ClinicalTrials.gov