Ventilatory Parameters in Predicting Outcomes in ARDS Patients

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age19-80
SponsorCentraCare

About this trial

This is a single-centre prospective observational study aimed to determine if Pocc (occlusion pressure at 100 msec), TCe ( Expiratory time constant ), Mechanical Stress power, Ventilatory ratio and C20/Cdyn would predict outcomes in patients with moderately severe ARDS (Acute respiratory distress syndrome), who are on mechanical ventilation

Eligibility criteria

Qualifiers

Patients with Acute respiratory failure needing mechanical ventilation

Diagnosis of Severe ARDS with severity: PF ratio < 150, with PEEP/CPAP > 5

Disqualifiers

r2 < 0.95, monitored on the ventilator

Expiratory flow that is not first-order or non-exponential decay

Patients with Nor-epinephrine requirements > 0.1 mcg/kg/min within 2 hours of intubation

Patients requiring ECMO ( Extracorporeal membrane oxygenation)

Trial design

Treatments tested in this trial

  • Poccl, Time constant, driving pressure

Treatment groups

No treatment groups listed

Sponsors and collaborators