Viral Infection of HSPC Impacts Hematopoiesis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssistance Publique - Hôpitaux de Paris
We propose to demonstrate that HIV-1 and SARS-CoV-2 are capable of targeting long-lived HSPC with self-renewal capacities. These progenitors, thus transformed into host cells, can give rise to a durable source of infected cells with an impact on hematopoiesis.
HIV-positive patients with a negative or positive viral load.
managed at Ambroise Paré Hospital.
patients with a bone marrow biopsy or myelogram performed as part of their care.
None