Viromes in Infants Presenting With a Septic Syndrome
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age0-3
SponsorUniversity Hospital, Montpellier
About this trial
Fever in infants younger than 3 months is a common reason for emergency department visits and is associated with a significant risk of serious bacterial infections. Because it is difficult to distinguish bacterial from viral infections at presentation, management is often aggressive and includes invasive procedures, hospitalization, and empiric antibiotic therapy.
Despite advances in molecular diagnostics, the etiology of fever remains unidentified in a substantial proportion of cases. This study aims to assess the presence of pathogenic viruses in respiratory and intestinal samples from febrile infants younger than 3 months compared with afebrile controls, and to explore associations with clinical, biological, environmental, and socio-economic factors
Eligibility criteria
Qualifiers
Age < 3 months
Fever ≥38°C confirmed in pediatric emergency department
Age < 3 months
Children requiring general anesthesia or managed in the pediatric emergency department, or during hospitalization or consultation, for a non-infectious condition requiring venipuncture
Disqualifiers
Lack of parental/legal guardian consent
Lack of affiliation with a social security scheme
Antibiotic treatment within 8 days prior to inclusion
Lack of parental/legal guardian consent
Trial design
Treatments tested in this trial
- biological samples
Treatment groups
130 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov