About this trial
The purpose of this study is to measure the feasibility, acceptability of virtual reality (VR) brain games and estimate their effect on memory, attention, and mood for ICU survivors. The VR program will be used at home through a headset and hand controls.
Eligibility criteria
Qualifiers
Adults aged 50 years or older
English speaking
Admitted to the intensive care unit (ICU) with acute respiratory failure/invasive mechanical ventilation
Screening positive for delirium (using Richmond Agitation Sedation Scale and Confusion Assessment Method for the ICU)
Disqualifiers
Acute neurologic injury such as stroke, traumatic brain injury, brain mass, intracranial hemorrhage, seizures, or central nervous system infection
Chronic cognitive or physical function deficit preventing participation in study interventions or assessments (determined by chart diagnoses and direct participant interview)
Chronic cognitive impairment (including mild cognitive impairment or dementia) identified by chart diagnosis, prescription of anti-dementia medications, or Informant Questionnaire on Cognitive Decline in the Elderly Score (IQCODE) >3.3 obtained from family caregiver
Severe, uncorrected vision or hearing impairment preventing participation in intervention or outcomes assessments
Trial design
Treatments tested in this trial
- VR-based cognitive training program
- VR-based attention control
Treatment groups
Sponsors and collaborators
Indiana University
Lead sponsor
Indiana University Health
Collaborator