Virus as Treatment of C. Difficile Infection (VISION)

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCopenhagen University Hospital, Hvidovre

About this trial

Fecal Virome Transplantation (FVT) has in small studies shown benefit in the treatment of recurrent C. difficile infection.

In the VISION study we will treat patients with recurrent C. difficile infection with FVT capsules and compare the treatment with Fecal Microbiota Transplantation (FMT) capsules. Both will be following af standard treatment of antibiotics (Vancomycin)

Eligibility criteria

Qualifiers

Recurrent C. difficile infection (first or second recurrence)

Understand danish

Disqualifiers

Serious food allergy (anaphylaxis)

Other pathogenic bacteria/virus in stool sample prior to inclusion

Inability to ingest capsules

Gastrointestinal perforation in the 180 days prior to inclusion

Trial design

Treatments tested in this trial

  • Fecal Virome Transplantation
  • Fecal microbiota Transplantation

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Copenhagen University Hospital, Hvidovre

Lead sponsor

University of Copenhagen

Collaborator