Virus Transmission to People Recently Bitten or With a History of Monkey Bites "SIMVIR

ConditionBites Monkey
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorInstitut Pasteur

About this trial

Nonhuman primates (NHPs) constitute an important reservoir of infectious agents, some of which have emerged in human populations as deadly pathogens. Human exposure to the biological fluids of NHPs - particularly through bites - can result in the transmission of several viruses. Only the rabies virus is currently targeted by post-exposure prophylaxis following an injury caused by an NHP.

The objective of the study is to investigate the prevalence of STLV-1 and SFV infections following a nonhuman primate bite.

Eligibility criteria

Qualifiers

Age ≥ 18 years

Bite inflicted by an HNP (WHO category 3 level)

Written informed consent

Affiliation with a social security scheme (excluding State Medical Aid

Disqualifiers

Patient presenting only with scratches inflicted by a PNH

Medical management incompatible with the objectives of the study

Patient who, in the doctor's opinion, is unlikely to comply with the study protocol

Health conditions are incompatible with the sample collection required by the study

Trial design

Treatments tested in this trial

  • Blood samples collection
  • Saliva samples collection

Treatment groups

80 Participants
are divided into 2 treatment groups

Sponsors and collaborators