About this trial
The goal of this project is to utilize stable isotopically labeled vitamin D3 and state of the art mass spectrometric methodology to assess vitamin D dynamics during pregnancy in relation to relation to obesity and vitamin D binding protein genotype. At the conclusion of this study, the investigators will have obtained novel information on the absorption and utilization of vitamin D in women and the degree to which vitamin D utilization during pregnancy is impacted by genetic ancestry, vitamin D binding protein concentration and genotype and by excess adiposity. The long-term goal is to better understand the unique metabolism of vitamin D during pregnancy.
Eligibility criteria
Qualifiers
Self-reported White and Black women
Age 20-39
Body mass index (BMI) 1or pre-pregnancy BMI (If currently pregnant) either 18.5-24.9 kg/m2 or greater than or equal to 30 kg/m2
Singleton pregnancy
Disqualifiers
BMI or pre-pregnancy BMI <18.5 kg/m2
Human immunodeficiency virus (HIV) infection
Diagnosed eating disorder
Malabsorption disease
Trial design
Treatments tested in this trial
- Vitamin D dynamics-pregnant
- Vitamin D dynamics-nonpregnant
Treatment groups
Sponsors and collaborators
Cornell University
Lead sponsor
University of Rochester
Collaborator