Vitamin D Dynamics in Women

ConditionPregnancy
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age20-39
SponsorCornell University

About this trial

The goal of this project is to utilize stable isotopically labeled vitamin D3 and state of the art mass spectrometric methodology to assess vitamin D dynamics during pregnancy in relation to relation to obesity and vitamin D binding protein genotype. At the conclusion of this study, the investigators will have obtained novel information on the absorption and utilization of vitamin D in women and the degree to which vitamin D utilization during pregnancy is impacted by genetic ancestry, vitamin D binding protein concentration and genotype and by excess adiposity. The long-term goal is to better understand the unique metabolism of vitamin D during pregnancy.

Eligibility criteria

Qualifiers

Self-reported White and Black women

Age 20-39

Body mass index (BMI) 1or pre-pregnancy BMI (If currently pregnant) either 18.5-24.9 kg/m2 or greater than or equal to 30 kg/m2

Singleton pregnancy

Disqualifiers

BMI or pre-pregnancy BMI <18.5 kg/m2

Human immunodeficiency virus (HIV) infection

Diagnosed eating disorder

Malabsorption disease

Trial design

Treatments tested in this trial

  • Vitamin D dynamics-pregnant
  • Vitamin D dynamics-nonpregnant

Treatment groups

160 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Cornell University

Lead sponsor

University of Rochester

Collaborator