Vomiting Prevention in Children With Cancer

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorThe Hospital for Sick Children

About this trial

The goal of this single arm trial is to learn if a machine learning (ML) model predicting the risk of vomiting within the next 96 hours will impact vomiting outcomes in inpatient cancer pediatric patients.

The main questions it aims to answer are whether an ML model predicting the risk of vomiting within the next 96 hours will:

Primary

1\. Reduce the proportion with any vomiting within the 96-hour window

Secondary

1. Reduce the number of vomiting episodes 2. Increase the proportion receiving care pathway-consistent care 3. Impact on number of administrations and costs of antiemetic medications

Newly admitted participants will have a ML model predict the risk of vomiting within the next 96 hours according to their medical admission information. The prediction will be made at 8:30 AM following admission. Pharmacists will be charged with bringing information about patients' vomiting risk to the attention of the medical team and implementing interventions.

Eligibility criteria

Qualifiers

All pediatric patients admitted to the oncology service at SickKids

Disqualifiers

Pediatric patients admitted to the oncology service at SickKids that are discharged prior to prediction time

Trial design

Treatments tested in this trial

  • ML-based intervention

Treatment groups

1,332 Participants
are divided into 1 treatment group

Sponsors and collaborators