About this trial
This is a randomized controlled trial to explore the efficacy and safety of washed microbiota transplantation (WMT) for diabetic gastroparesis (DGP) patients.
Eligibility criteria
Qualifiers
Diagnosed with diabetes for over 1 year;
Accompanied by symptoms such as abdominal bloating, early satiety, persisting for at least 3 months, with a GCSI Total Score greater than/equal to 2.3;
Objective evidence of delayed gastric emptying within the past 3 months, including but not limited to scintigraphic gastric emptying or gastric ultrasound;
Upper gastrointestinal obstructive lesions were ruled out by imaging or endoscopic examination within the past 3 months;
Disqualifiers
Have any upper gastrointestinal pathology other than diabetic gastroparesis that would require therapy other than that provided in this trial;
Have a prior history of gastric surgery, including but not limited to gastric bypass, gastrectomy, gastric banding, pyloroplasty, fundoplication, or vagotomy in past 1 year;
Have any organic/neurological disease that is suspected to be causing gastroparesis, other than diabetes;
Have been using medications affecting gastrointestinal motility, such as GLP-1 agonists;
Trial design
Treatments tested in this trial
- washed microbiota transplantation
- placebo