About this trial
A national cohort study with all patients scheduled for neoadjuvant treatment with (chemo)radiotherapy or short course radiotherapy with delayed surgery 6-8 weeks) for rectal cancer staged as cT4bNX/anycTanycN and cMRF+/anycTanycN and lateral lymph nodes on MRI (and patients that have been offered short course raditotherapy with delayed surgery due to various reasons). The tumours are positioned midrectal or low and are palpable with the finger. The patients offered this treatment after recommendations on their local multidisciplinary tumour board will be will be informed and offered to participate in the study. Patients scheduled for short course radiotherapy with immediate surgery cannot be included.
Eligibility criteria
Qualifiers
cT4bNX
anycTanycN and cMRF+ anycTanycN and lateral lymph nodes on MRI
Disqualifiers
No informed consent received for participation.
Patients with rectal cancer that is scheduled for (chemo) radiotherapy but is not palpable during rectal examination (10-15 cm) as this cannot be examined by digital examination and followed as scheduled.
Contraindication for MRI such as presence of non compatible metallic implants or claustrophobia.
Trial design
Treatments tested in this trial
- endoscopy
- Surgery
- MRI
Treatment groups
Sponsors and collaborators
Sahlgrenska University Hospital
Lead sponsor
Karolinska Institutet
Collaborator