Weaning From Mechanical Ventilation After Pediatric Cardiac Surgery
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age2-10
SponsorAlexandria University
About this trial
Weaning from mechanical ventilation post congenital cardiac surgery is often challenging. It is well known that not all patients can be early extubated, although most are suitable for early postoperative weaning and extubating despite complex operative procedures. With advances in anaesthesia management, cardiopulmonary bypass (CPB), and surgical techniques, the trend of 'fast tracking', and early extubating of pediatrics postcardiac surgery seems to be feasible. Unnecessary prolonged mechanical ventilation increases the complication risks as airway trauma, ventilator associated pneumonia, and increased hospital stay
Eligibility criteria
Qualifiers
Age 2-10years.
Both sex.
after fulfilling weaning criteria
being pain free (observational pain/discomfort scale < 4). the weaning criteria; which include: low mandatory ventilator rate [6-8] or less; fraction of inspired oxygen (FIO2) ≤ 40; level of positive end expiratory pressure (PEEP) [3-5 cmH2O] guided by pressure/volume loop; reversal of the cause of postoperative mechanical ventilation; oxygenation index (OI) (mean air way pressure × FIO2/PaO2) < 5; dynamic compliance (Cdyn) > 1 ml/ cmH2O/kg
Disqualifiers
Duration of mechanical ventilation is more than 48 hours
Patients on high inotropic support (unstable hemodynamics)
Patients with disturbed conscious level
Patients with palliative cardiac shunting procedures (e.g., BT shunt, Glenn shunt).
Trial design
Treatments tested in this trial
- group P:pressure support ventilation mode
- group A:automatic tube compensation (ATC).
Treatment groups
34 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov