Western Sydney Kidney Injury Biopsy Study
ConditionKidney Injury
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorWestern Sydney Local Health District
About this trial
The investigators aim to develop a clinically validated, histological acute tubular injury (ATI) scoring system to help improve diagnostic precision and predict clinical outcomes following ATI.
To use an unbiased, data-driven approach, correlating pathological features (including digital pathology), key signatures using spatial technologies (transcriptomics or proteinomics) with relevant clinical outcomes. Spatial technologies (including spatial transcriptomics and spatial proteinomics) allow the use of 'precision pathology' to study the critical link between molecular characteristics to histological structure.
Eligibility criteria
Qualifiers
Had a kidney biopsy (native kidney or transplant kidney included) after year 2000
Kidney biopsy sample sent to Westmead Hospital for clinical interpretation
Disqualifiers
Patients who have never had a kidney biopsy performed
Biopsy sample not available at Westmead Hospital
No information on kidney function (serum creatinine or eGFR)
Trial design
Treatments tested in this trial
- Retrospective review of histological features
Treatment groups
1,000 Participants
are divided into 3 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov