Within-Individual Variability of Resting Metabolic Rate Over 12 Weeks
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorTel Aviv University
About this trial
This prospective observational study aims to characterize within-individual variability in resting metabolic rate (RMR) over a 12-week period using high-frequency repeated measurements under standardized conditions. Participants will undergo RMR assessments three times per week using whole-room indirect calorimetry.
The study will quantify the magnitude of physiological variability in RMR, distinguish true biological variation from measurement error, and estimate the minimal detectable change required to identify meaningful metabolic adaptations.
Eligibility criteria
Qualifiers
Adults aged 18-65 years
Clinically healthy individuals
Stable body weight (±2 kg) over the past 3 months
Ability and willingness to attend morning measurements three times per week for 12 weeks
Disqualifiers
Known uncontrolled endocrine or metabolic disease
Use of medications known to significantly affect resting metabolic rate (e.g., systemic corticosteroids, unstable thyroid hormone therapy)
Acute illness within 14 days prior to enrollment
Pregnancy or lactation
Trial design
Treatments tested in this trial
- Repeated Measurement of Resting Metabolic Rate
Treatment groups
30 Participants
are divided into 1 treatment groupLocations
Sponsors and collaborators
Source ClinicalTrials.gov