Wound Healing and Patient-Reported Outcomes After Gingival Graft Harvesting From the Palate

ConditionPalatal Wound
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversitat Internacional de Catalunya

About this trial

The goal of this clinical trial is to evaluate whether two different techniques for treating palatal wounds-sutures and cyanoacrylate bioadhesive-can influence postoperative morbidity, clinical healing, and soft tissue dimensional changes in patients undergoing epithelialized gingival graft harvesting from the palate. The main questions it aims to answer are:

Does the use of cyanoacrylate bioadhesive reduce postoperative morbidity compared to sutures? Does the choice of wound treatment technique affect clinical healing and three-dimensional changes in soft tissues? Researchers will compare the sutures (control group) to the cyanoacrylate bioadhesive (test group) to determine if the bioadhesive leads to improved postoperative outcomes.

Participants will:

Undergo epithelialized gingival graft harvesting from the palate. Receive either sutures or cyanoacrylate bioadhesive for wound closure. Be monitored for postoperative morbidity, clinical healing, and soft tissue dimensional changes.

Eligibility criteria

Qualifiers

Systemically healthy individuals older than 18 years old;

Healthy periodontal status according to the AAP/EFP definition;

Full-mouth plaque (FMPS) and bleeding scores (FMBS) ≤ 20%;

No history of soft tissue harvesting.

Disqualifiers

Pregnancy or lactation;

Self-reported smoking ≥10 cigarettes/day;

Metabolic diseases that negatively affect soft tissue healing (i.e., diabetes mellitus);

Any medication that may interfere with wound healing;

Trial design

Treatments tested in this trial

  • Suture
  • Cyanoacrylate bioadhesive

Treatment groups

66 Participants
are divided into 2 treatment groups