In order to reduce the clinical demand for kidney dialysis rate of Diabetic Kidney Disease（DKD） patients, a bidirectional cohort study of 4472 patients with DKD (Qi deficiency and collateral stasis syndrome) was carried out based on a preliminary DKD cohort of 13,000 patients. The exposure factor was supplementing and reducing the kidney turbidity-Huoxue Tongluo method represented by the addition and subversion of Shenzhuo prescription, and the incidence of end-stage renal disease was the main therapeutic index. Follow-up was conducted for 2 years
1 in line with Western medicine diagnostic criteria for type 2 diabetic kidney disease ;
2 18-80 years old, regardless of gender ;
3 eGFR > 15ml / ( min · 1.73m2 ) ; the eGFR was calculated according to the chronic kidney disease epidemiology collaboration equation ( CKD-EPI ).
4 In line with the diagnostic criteria of qi deficiency and collateral stasis syndrome in traditional Chinese medicine ;
1 combined with other clear renal diseases, such as polycystic kidney disease, glomerulonephritis, renal tumor, etc. ;
2 patients with a history of recurrent genitourinary tract infection ;
3 combined with cardiovascular and cerebrovascular, digestive, respiratory, urinary, immune system serious diseases or mental diseases ;
4 currently in pregnancy, lactation, or pregnancy plan women ;
Liu Hongfang
Lead sponsor
Dongzhimen Hospital, Beijing
Sponsor institution
Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Collaborator
First Affiliated Hospital, Sun Yat-Sen University
Collaborator
Tianjin Medical University
Collaborator
Changchun University of Chinese Medicine
Collaborator
EFONG PHARMRCEUTICRL
Collaborator
Xinxiang Central Hospital of Henan province
Collaborator
Xiamen Hospital of Traditional Chinese Medicine
Collaborator
Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
Collaborator
Beijing Tiantan Hospital
Collaborator
Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine
Collaborator
Hubei Zhongshan Hospital Affiliated to Wuhan University
Collaborator