Status: Recruiting
A Randomized Trial of Delayed Radiotherapy in Patients Low-grade Oligodendrogliomas Requiring a Treatment Other Than Surgery
Because of their prolonged survival, patients with 1p/19q-codeleted low-grade oligodendrogliomas treated with RT + PCV are at risk of neurocognitive deterioration. We make the hypothesis that withholding radiotherapy until tumor progression could reduce the risk of neurocognitive deterioration without impairing overall survival.
Participants needed: 280
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Hospices Civils de LyonUpdated: Jan 29, 2026Locations: 26
Eligibility criteria
Tumor is co-deleted for 1p and 19q based and IDH-mutant (IDH1 or IDH2) according... [+17]
Pregnant and nursing women [+11]