Abortion, Second Trimester

2

Review clinical trials related to Abortion, Second Trimester. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Cervical Preparation for Same-Day Dilation & Evacuation

This is a noninferiority randomized control trial of two cervical preparation methods prior to same-day Dilation \& Evacuation (D\&E). Cervical preparation is a process that softens and dilates the cervix prior to a procedure. The primary objective is to evidence noninferiority of cervical preparation using a single-balloon catheter method when compared to a group receiving osmotic dilators, specifically in D\&E operative time. Secondary objectives will compare the two methods for adequate dilation, ability to complete the operation in the same day, participant pain, satisfaction and safety.

Participants needed: 32
Trial details
Age: 16+Biological sex: FemaleType: InterventionalSponsor: Boston Medical CenterUpdated: Jun 30, 2026Locations: 1
Eligibility criteria

Between 16 weeks 0 days - 18 weeks 6 days gestational age who are pursuing termi... [+3]

Allergy to betadine, aquacryl hydrogel, latex-free silicone single-balloon cathe... [+4]

Status: Recruiting

Foley Balloon for Cervical Preparation Before Dilation and Evacuation

To evaluate the Foley Balloon technique for cervical preparation before second trimester surgical abortion between 16 and 21 weeks estimated gestational age in combination with misoprostol to prepare the cervix before dilation and evacuation (D\&E) instead of osmotic dilators (Laminaria). Specific Aim One: Assess definitively whether using a Foley Balloon and Misoprostol is non-inferior to osmotic dilators for cervical preparation before D\&E. Specific Aim Two: Evaluate patient satisfaction with the two methods of second trimester abortion. Specific Aim Three: Evaluate provider satisfaction with the two methods of second trimester abortion.

Participants needed: 102
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Stony Brook UniversityUpdated: Apr 30, 2026Locations: 1
Eligibility criteria

Women 18 years and older presenting to Hospital Central de Maputo requiring abor... [+1]

Less than age 18 [+10]