Achilles Tendon

4

Review clinical trials related to Achilles Tendon. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Morphological and Mechanical Assessment in the Achilles Tendon After Radiofrequency Stimulation in Runners

448 kHz capacitive-resistive monopolar radiofrequency is an emerging physiotherapy technique whose usefulness and clinical relevance still need to be investigated. This study is a pre-post quasi-experimental study in which several variables will be measured before and immediately after 448 kHz capacitive resistive monopolar radiofrequency. It aims to analyze the morphological and mechanical changes in the Achilles tendon following the intervention in healthy runners.

Participants needed: 19
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: University of MalagaUpdated: Jun 17, 2026Locations: 1
Eligibility criteria

Adults aged 18-65 [+2]

History of lower limb surgery, rheumatic or neuromuscular diseases or pregnancy [+2]

Status: Not yet recruiting

CUHK Achilles Tendon Disorder Registry

This is a long-term research registry for patients with Achilles tendon disorders (like tears, chronic pain, or ruptures) as well as healthy adults without tendon problems. The goal is to collect detailed information over time to understand which treatments work best for different people, identify risk factors for injury, and improve overall care. Adults over 18, both with and without Achilles tendon conditions, are eligible to join. Participants will attend several assessment visits at the Prince of Wales Hospital over the first year (at the start, 6 weeks, 3, 4, 6, and 12 months) for physical tests, ultrasounds, and questionnaires. After the first year, follow-up continues with annual online questionnaires for up to five years. The main measure is a standard questionnaire about tendon pain and function (VISA-A). The study aims to use this information to guide better, more personalized rehabilitation strategies, improve patient outcomes, and reduce long-term disability. All participation is voluntary and requires written consent.

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Chinese University of Hong KongUpdated: Jan 9, 2026Duration: 5 Years
Eligibility criteria

Adults (>18 years of age)

Any physical or psychological comorbidity that would impair the ability to compl... [+1]

Status: Not yet recruiting

Validity and Reliability of Calf Raise Tests in Patients With Achilles Tendon Rupture and Lateral Ankle Sprain

This study aims to evaluate the validity and reliability of clinically used Calf Raise Test parameters (collected with the "the Calf Raise App") between patients with Lateral Ankle Sprain or Achilles Tendon Repair and healthy controls.

Participants needed: 70
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Schulthess KlinikUpdated: Sep 29, 2025
Eligibility criteria

Signed informed consent [+2]

Chronic Ankle Instability (defined by symptoms such as giving way, perceived ins... [+5]

Status: Recruiting

Effects of the Menstrual Cycle on Triceps Surae Properties in Women

The menstrual cycle is an important biological rhythm, whereby large cyclic fluctuations in endogenous sex hormones, such as estrogen and progesterone, are observed, which can affect performance. Evidence shows that endogenous and exogenous changes in hormone concentrations during the menstrual cycle exert many effects on the nervous and endocrine systems, in addition to the connective tissue, with consequences for the movement system. Pre-clinical studies (i.e., in animal models) show an estrogen association with the structural and mechanical properties of tendons and ligaments. Several elegant studies performed with female participants have tried to establish the mechanism underlying the effect of estrogen on collagen synthesis and its effects on exercise and functionality. Their findings suggest that the tendon properties may be affected when exposed to varying concentrations of estrogen. The largest tendon in humans, the Achilles tendon, has a direct role in functional capacity, activities of daily living, and locomotion. Studies show that the triceps surae's structural and mechanical properties may change throughout the menstrual cycle, and that these changes are related to endogenous and exogenous fluctuations in estrogen and progesterone. Musculotendinous stiffness, which is dependent on the collagen content, has been seen to vary considerably over the course of the menstrual cycle. In addition, it has been reported that females who have been taking the contraceptive pill for at least a year demonstrate lower levels of tendon strain compared to non-pill taking females, indicating a possible influence of hormonal state on tendon mechanical properties. However, the different experimental designs, the varied approaches to the evaluations and the lack of studies with high methodological quality limit our understanding of the effects of the different phases of the menstrual cycle on the triceps surae's neuromechanical properties. The aim of this observational study will be to investigate whether the morphological, mechanical (active and passive), material, and functional properties of the plantar flexor muscles and of the Achilles tendon, as well as functional parameters, change during voluntary contractions throughout the phases of the menstrual cycle in eumenorrheic women and in users of hormonal contraception. Understanding the acute effects of these properties in eumenorrheic women and users of hormonal contraception is essential so that we can adequately plan interventions and prescriptions of physical exercise and rehabilitation aimed for women.

Participants needed: 40
Trial details
Age: 18-30Biological sex: FemaleType: ObservationalSponsor: Marco Aurélio Vaz, PhDUpdated: Jun 10, 2024Locations: 1
Eligibility criteria

Inclusion criteria for the group of eumenorrheic women [+17]

Women who have anovulatory cycles or phase lutea deficiency. [+8]