Status: Recruiting
Comparing Post-Transplant Cyclophosphamide As GVHD Prophylaxis to Standard of Care for Acute Leukemia Patients
This randomized clinical trial will evaluate two approaches of GvHD prophylaxis; the standard of care GVHD prophylaxis regimen (methotrexate/calcineurin inhibitors) and post-transplant cyclophosphamide with calcineurin inhibitors for their efficacy as a new GVHD prophylaxis strategy.
Participants needed: 264
Trial details
Phase: Phase 3Age: 14-65Biological sex: AllType: InterventionalSponsor: King Faisal Specialist Hospital & Research CenterUpdated: Mar 13, 2025Locations: 1
Eligibility criteria
Patients with Acute Leukemias (AML, ALL) in morphologic complete remission with... [+7]
Karnofsky or Lansky Performance Score < 70%. [+10]