Acute Malnutrition With no Complications

2

Review clinical trials related to Acute Malnutrition With no Complications. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Effectiveness of an Alternative Protocol in the Management of Acute Malnutrition

This experimental study aims to test an alternative protocol for managing acute malnutrition in children aged 6-59 months in Burkina Faso. This alternative protocol consists of using RUTF instead of RUSF for the management of moderate acute malnutrition and reduced-dose RUTF instead of standard-dose RUTF for the treatment of severe acute malnutrition. The main questions are: 1. Does treating children with moderate acute malnutrition using RUTF lead to a non-inferior programmatic and sustained recovery rate compared to the standard care with RUSF? 2. Does treating children with uncomplicated severe acute malnutrition using a reduced dose of RUTF lead to a non-inferior programmatic and sustained recovery rate compared to the standard care with a standard dose of RUFT? Secondly, the study will investigate the effect of this alternative protocol compared to the standard protocol on cost-effectiveness, psychomotor development, weight and linear growth and incidence of relapses.

Participants needed: 3,521
Trial details
Age: 6-59Biological sex: AllType: InterventionalSponsor: Institut de Recherche en Sciences de la Sante, Burkina FasoUpdated: Jan 24, 2025Locations: 1
Eligibility criteria

MAM [+5]

Failure of appetite test [+21]

Status: Not yet recruiting

Microbiome-Directed Food for Sustained Recovery From Acute Malnutrition

The goal of this experimental study is to test the efficacy of a new formulation - The microbiome-directed food (MDF) to treat acute malnutrition among children aged 6 to 23 months. The main questions are: * Does treating children with moderate or severe uncomplicated malnutrition using MDF leads to higher programmatic recovery rate compared to standard of care ? * Does treating children with moderate or severe uncomplicated malnutrition using MDF leads to higher sustained recovery rate compared to standard of care ? The MDF will be compared to Ready-to-use supplementary food (RUSF) for moderately malnourished children, and to Ready-to-use therapeutic food (RUTF) for severely malnourished children to see the effects on recovery and sustained recovery rate.

Participants needed: 6,200
Trial details
Age: 6-23Biological sex: AllType: InterventionalSponsor: Institut de Recherche en Sciences de la Sante, Burkina FasoUpdated: Mar 13, 2024Locations: 1
Eligibility criteria

Age between 6 and 23 months [+1]

Bilateral pitting edema [+7]