Health Trials

Acute Migraine

2

Review clinical trials related to Acute Migraine. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine

This is a long-term safety study to evaluate the safety and tolerability of intermittent use of elismetrep in the acute treatment of migraine attacks.

Participants needed: 1,000
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Kallyope Inc.Updated: Jul 2, 2026Locations: 115
Eligibility criteria

Participant completing an acute treatment trial of elismetrep (Study K-304 P003;... [+6]

Is a female who is pregnant, breast-feeding, or intends to become pregnant durin... [+8]

Read more
Status: Not yet recruiting

A Prospective, Open-Label Study Evaluating the Effectiveness of Gepants for Acute Treatment of Migraine in the Emergency Department

Prospective, single-site, open-label, non-controlled pilot study consisting of two parallel trials. Participants will receive rimegepant or zavegepant for acute migraine treatment during a single Emergency Department visit, with post-discharge follow-up through 28 days. Participants will be allocated to either the rimegepant trial or the zavegepant trial. The study design does not include a placebo or active comparator control group, and the two gepant study drugs are not designed to function as active comparator groups. The objective in this investigation is to examine relief from either rimegepant or zavegepant in separate parallel trials.

Participants needed: 100
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: University of South FloridaUpdated: Jun 25, 2026Locations: 1
Eligibility criteria

• At least 18 years of age [+4]

• Use of intranasal decongestants within 1 hour prior to study drug administrati... [+14]

Read more