Health Trials

Acute Myeloid Leukemias

2

Review clinical trials related to Acute Myeloid Leukemias. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study of Revumenib in Combination With Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia (AML) With a NPM1 Mutation

The purpose of this study is to assess if adding revumenib to standard chemotherapy improves outcomes in participants with AML with certain genetic mutations compared to chemotherapy alone. The study will also assess the safety of adding revumenib to chemotherapy.

Participants needed: 468
Trial details
Phase: Phase 3Age: 12+Biological sex: AllType: InterventionalSponsor: Syndax PharmaceuticalsUpdated: Jun 24, 2026Locations: 52
Eligibility criteria

Participants must have newly diagnosed and previously untreated AML and be candi... [+5]

Diagnosis of active acute promyelocytic leukemia. [+7]

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Status: Recruiting

A Phase 1 Study of STX-0712 in Patients With Advanced Hematological Malignancies (CMML and AML)

This is a first-in-human, multicenter, open-label, phase 1 study to evaluate the safety, PK, PD and preliminary efficacy of STX-0712 in patients with advanced CMML and AML for whom there are no further treatment options known to confer clinical benefit.

Participants needed: 105
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Solu Therapeutics, IncUpdated: Feb 9, 2026Locations: 7
Eligibility criteria

Refractory/resistant CMML, defined as: Diagnosis of CMML 1 or 2; and has not res... [+7]

Has any of the following disease-specific conditions: For CMML: Myelodysplastic... [+15]

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