Status: Recruiting
Surufatinib and Sintilimab in Combination With Capecitabine for Metastatic Adenocarcinoma of Small Intestine or Appendix Carcinoma
To explore the safety and efficacy of Surufatinib and Sintilimab in Combination With Capecitabine in Patients With Previously Treated Metastatic Adenocarcinoma of Small Intestine or Appendix Carcinoma : a Single-arm, a Single-center , Phase 2 Trial. Meanwhile, Exploring the maximum tolerant dose or recommended II research dose of Surufatinib combined with a fixed dose of Sintilimab and Capecitabine using 3 + 3 dose climbing experiment.
Participants needed: 36
Trial details
Phase: Phase 2Age: 18-70Biological sex: AllType: InterventionalSponsor: Sun Yat-sen UniversityUpdated: Dec 17, 2025Locations: 1
Eligibility criteria
Histological or cytological documentation of adenocarcinoma of Small Intestine o... [+7]
Prior treatment with Surufatinib [+8]