Adhesive Capsulitis of the Shoulder

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Review clinical trials related to Adhesive Capsulitis of the Shoulder. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

OMT for Adhesive Capsulitis

The goal of this clinical trial is to learn if Osteopathic Manipulative Treatment (OMT) is an effective addition to treatment of adhesive capsulitis. OMT is a non-invasive treatment in which a doctor gently moves and stretches muscles, joints, and tissues manually. Adhesive capsulitis is more commonly known as "frozen shoulder" and describes a shoulder that becomes stiff, painful, and limited in its motion due to some structural change in the joint. The main questions it aims to answer are: Is recovery faster when OMT is added to regular treatment? Are patients that underwent OMT more satisfied with their treatment? Researchers will compare patients who underwent OMT to patients who did not to see if OMT is an effective additional treatment for frozen shoulder. Participants will: * Be assigned to one of the four experimental groups * Visit clinic and/or physical therapy to undergo the treatments associated with their group: 1. standard course of prescribed physical therapy 2. standard course of prescribed physical therapy and an injection of an anti-inflammatory and anesthetics in the shoulder 3. standard course of prescribed physical therapy and (up to) 4 OMT sessions 4. standard course of prescribed physical therapy, an injection of an anti-inflammatory and anesthetics in the shoulder, and (up to) 4 OMT sessions. * Visit clinic 1 month, 3 months, 6 months, and 1 year after treatment is complete * Complete a survey about how satisfied they are with their treatment 1 month, 3 months, 6 months, and 1 year after it is complete

Participants needed: 300
Trial details
Phase: Phase 4Age: 18-89Biological sex: AllType: InterventionalSponsor: University Hospitals Cleveland Medical CenterUpdated: Jun 9, 2026Locations: 3
Eligibility criteria

patients diagnosed with adhesive capsulitis who have not received prior treatmen...

patients with contraindications to corticosteroid injections (uncontrolled diabe... [+1]

Status: Recruiting

Frozen Shoulder and Hormone Replacement Therapy

The purpose of this study is to determine the effects of hormone replacement therapy (HRT) in addition to standard treatment on frozen shoulder symptoms in women with age-related changes to their menstrual cycle. Frozen shoulder refers to the condition a doctor diagnosed the participant with regarding shoulder pain, stiffness, and progressive loss of range of motion. Age-related menstrual cycle changes, known as perimenopause and/or menopause, refers to a change or stoppage of monthly menstrual cycles. Other symptoms participants may be experiencing include vaginal dryness, hot flashes, or night sweats. Hormone replacement therapy (HRT) refers to medicine with female hormones in it. For this study, HRT will be in the form of a patch that goes on the skin and a daily oral pill. Participants will be randomly assigned to receive either HRT plus standard care, or only standard care. Follow-up tests will be completed at 6 months of treatment to assess participant progress.

Participants needed: 60
Trial details
Phase: Phase 4Age: 40+Biological sex: FemaleType: InterventionalSponsor: University of California, San FranciscoUpdated: Jun 8, 2026Locations: 1
Eligibility criteria

Diagnosis of adhesive capsulitis of the shoulder

History of hormone sensitive cancer [+2]

Status: Recruiting

Transcatheter Arterial Embolization Using Nexsphere-F for Chronic Shoulder Pain Refractory to Conservative Treatment

Evaluation of the efficacy and safety of transcatheter arterial embolization using 'Nexsphere-F' for pain relief in patients with adhesive capsulitis of the shoulder joint that does not respond to conservative treatment. This study aims to investigate the efficacy and safety of transcatheter arterial embolization using embolic agents in patients with adhesive capsulitis of the shoulder joint. This is a single-center, prospective, open-label, randomized clinical trial.

Participants needed: 44
Trial details
Age: 19-85Biological sex: AllType: InterventionalSponsor: Chung-Ang University Hosptial, Chung-Ang University College of MedicineUpdated: May 19, 2026Locations: 1
Eligibility criteria

Patients who have voluntarily signed a written informed consent form after recei... [+4]

Patients with a history of surgery on the shoulder joint targeted for the clinic... [+4]

Status: Not yet recruiting

Effectiveness and Efficiency of an Upper Limb Active-Passive Exoskeleton Robot in Patients With Frozen Shoulder

Frozen shoulder, also known as adhesive capsulitis, is a common chronic shoulder disorder with symptoms including shoulder pain, limitations in both active and passive range of motion, and muscle weakness, which significantly affects daily functional abilities. The investigator applied upper limb exoskeleton-assisted therapy. This experiment used a randomized controlled trial to assess the clinical rehabilitation effects of exoskeleton-assisted range of motion and resistance training on patients with frozen shoulder.

Participants needed: 40
Trial details
Age: 20+Biological sex: AllType: InterventionalSponsor: China Medical University HospitalUpdated: Mar 25, 2026Locations: 1
Eligibility criteria

Patients diagnosed by a clinician with frozen shoulder or adhesive capsulitis in... [+1]

Individuals with osteoarthritis or other skeletal conditions of the shoulder joi... [+6]

Status: Not yet recruiting

Capsular Distension Versus Corticosteroid Injection in Adhesive Capsulitis

Adhesive capsulitis is a common and disabling shoulder condition characterized by pain and progressive limitation of range of motion. Capsular distension and intra-articular corticosteroid injection are commonly used therapeutic options, often combined with rehabilitation, but their comparative effectiveness remains debated. The objective of this randomized controlled trial is to compare the efficacy and tolerance of ultrasound-guided capsular distension combined with rehabilitation versus intra-articular corticosteroid injection combined with rehabilitation in patients with adhesive capsulitis. Outcomes will include shoulder pain, range of motion, functional disability, patient satisfaction, and procedure-related complications, assessed at short, mid, and long-term follow-up.

Participants needed: 50
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Faculty of Medicine of TunisUpdated: Mar 25, 2026Locations: 1
Eligibility criteria

Age between 18 and 80 years [+4]

Rotator cuff tear [+13]

Status: Not yet recruiting

Anterior vs Posterior vs Combined Intra-Articular Injections for Adhesive Capsulitis

This randomized controlled clinical trial aims to compare the efficacy of three different intra-articular injection approaches (anterior, posterior, and combined anterior-posterior) in patients with adhesive capsulitis of the shoulder. Thirty participants will be randomly assigned to one of three groups and treated with a standardized injection solution consisting of corticosteroid, lidocaine, and saline. Clinical outcomes will be evaluated using pain scores, functional scales, and imaging parameters.

Participants needed: 30
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Aslinur Keles Ercisli, MD, PhDUpdated: Jan 23, 2026
Eligibility criteria

Not listed

Status: Recruiting

Dose Efficacy in Adhesive Capsulitis

The purpose of this study is to find out if the treatment of adhesive capsulitis with 40 mg of methylprednisolone in combination with a hydrodilatation is comparable to 80 mg of methylprednisolone for pain reduction, improving shoulder mobility, and reducing side effects. Researchers will enroll 40 people in this study which is taking place solely at the Toronto Rehabilitation Institute, University Avenue. This study should take approximately 12 months to complete and the results should be known in about 15 to 18 months. During this study, patients will receive an ultrasound guided shoulder hydrodilatation combined with corticosteroid after "randomized" into one of the groups (40 mg vs 80 mg). This is a double blind study as both patients and physicians would not know the group patient was randomized to. Pain scores, Range of Motion and few other questionnaires wold be completed to track the response to the interventions at baseline prior to injection, four weeks after the procedure and 3 months after the procedure.

Participants needed: 40
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: University Health Network, TorontoUpdated: Feb 27, 2025Locations: 1
Eligibility criteria

>18 years of age [+1]

Injection received in the affected shoulder < 3 months ago (any kind) [+9]

Status: Recruiting

Effectiveness of Instrumental Rehabilitation in Patients With Adhesive Capsulitis

The aim of this study is to evaluate the effectiveness of robotic training compared to conventional rehabilitation in patients with AC.

Participants needed: 70
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Mohammed V Souissi UniversityUpdated: Feb 3, 2025Locations: 1
Eligibility criteria

Patients >18 years of age [+2]

Cognitive impairment [+7]

Status: Recruiting

Evaluation and Treatment of Adhesive Capsulitis Using Non-invasive Neurostimulation Devices

The goal of this randomized controlled trial is to compare the integrity of somatosensory processing with transcranial magnetique stimulation (TMS) and corticospinal excitability of the affected shoulder in individuals with adhesive capsulitis versus healthy controls. The secondary objective is to compare the clinical and neurophysiological effects of an intervention using tendon vibration (VIB) to induced kinesthetic illusions. This will involve comparing two groups: one receiving a real intervention versus a placebo intervention protocol, both coupled with standardized exercises in individuals with capsulitis. The hypotheses are that the proprioceptive processing and corticospinal excitability are impaired in the presence of capsulitis, and that the VIB + exercises intervention will result in greater improvements than the placebo VIB + exercises. To goal is to establish the first empirical foundations for understanding adhesive capsulitis, using cutting-edge neurophysiological investigation technologies. TMS will be used to explore the presence of maladaptive plasticity in motor networks by assessing the excitability and integrity of the primary motor cortex (M1) and the corticospinal tract. Recruitement: 30 healthy participants and 30 participants with a diagnosis of adhesive capsulitis will undergo 2 baselines assesments, 6 interventions with tendon vibration and 2 follow-up evaluation. Participants will be age- and sex-matched. Baseline and follw-up include: * Questionnaires : SPADI, QuickDASH, French version of the Mcgill Pain Questionnaire; * Active and passive range of motion; * Ultrasound for diagnosing capsulitis. Comparison parameters: * active motor threshold (aMT) * Motor evoked potential (MEP) latency and amplitude * Standardized kinesthetic illusion procedure (SKIP) : direction of illusion, clearness, amplitude/speed. Interventions : * 2 baselines including all questionnaires, ultrasound, active and passive range of motion, TMS procedure and SKIP; * 2 VIB interventions per week, for 3 weeks * Real VIB : 80Hz of vibration to induce kinesthetic illusions, * Placebo VIB : 40Hz of vibration that does not induce kinesthetic illusions * 2 follow-up including all questionnaires, ultrasound, active and passive range of motion, TMS procedure and SKIP.

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Université du Québec à ChicoutimiUpdated: Jan 28, 2025Locations: 1
Eligibility criteria

18 years old and over [+3]

Cognitive disorders; [+6]