Health Trials

AdV Infection

2

Review clinical trials related to AdV Infection. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Phase 3 Randomized Trial for Refractory ADV or CMV Infection With Family Matched CTLs and Standard of Care (SOC) vs SOC Alone

Patients with refractory ADV or CMV infection post allogeneic stem cell transplant will be randomized to either Family donor-derived viral specific cytotoxic T lymphocytes (CTLs) plus standard of care (SOC) vs SOC alone.

Participants needed: 69
Trial details
Phase: Phase 3Age: 1-30Biological sex: AllType: InterventionalSponsor: New York Medical CollegeUpdated: Nov 10, 2025
Eligibility criteria

Consent: written informed consent given (by patient or legal representative) pri... [+7]

Patient with acute GVHD > grade 2 or moderate or extensive chronic GVHD at the t... [+8]

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Status: Recruiting

Multivirus-specific T-cell Transfer Post SCT vs AdV, CMV and EBV Infections

Haematopoietic stem cell transplantation (HSCT) can expose patients to a transient but marked immunosuppression, during which viral infections are an important cause of morbidity and mortality. Adoptive transfer of virus-specific T cells is an attractive approach to restore protective T-cell immunity in patients with refractory viral infections after allogeneic HSCT. The aim of this Phase III trial is to confirm efficacy of this treatment in children and adults.

Participants needed: 149
Trial details
Phase: Phase 3Age: 2+Biological sex: AllType: InterventionalSponsor: Tobias FeuchtingerUpdated: Jul 18, 2025Locations: 33
Eligibility criteria

Adult or paediatric patients (> 2 months of age) after allogeneic stem cell tran... [+2]

Patient with acute GvHD > grade II or extensive chronic GvHD at the time of IMP... [+11]

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