Health Trials

Advanced Refractory Solid Tumors

2

Review clinical trials related to Advanced Refractory Solid Tumors. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Cetuximab β Combined With PRaG Regimen in the Treatment of EGFR-positive Advanced Refractory Solid Tumors

This study is a single-arm, multi-center, prospective clinical study aimed at exploring the efficacy and safety of cetuximab β combined with PRaG regimen in rescuing patients with EGFR-positive advanced refractory solid tumors.

Participants needed: 40
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Second Affiliated Hospital of Soochow UniversityUpdated: Jan 8, 2026Locations: 1
Eligibility criteria

Voluntarily sign a written informed consent form; [+6]

Pregnant or breastfeeding women； [+9]

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Status: Recruiting

Selinexor & Talazoparib in Advanced Refractory Solid Tumors; Advanced/Metastatic Triple Negative Breast Cancer (START)

This is a single arm, open-label, phase I dose finding study, followed by a phase II expansion study. Phase I will be carried out in a modified 3+3 dose escalation design, with a projected enrolment of 33 patients with refractory solid tumors to determine the RP2D. In the phase II portion, a total of 30 patients with advanced/metastatic TNBC will be enrolled.

Participants needed: 63
Trial details
Phase: Phase 1, Phase 2Age: 18-99Biological sex: AllType: InterventionalSponsor: National University Hospital, SingaporeUpdated: Jul 25, 2025Locations: 1
Eligibility criteria

All patients must sign an informed consent in accordance with local institutiona... [+6]

Measurable disease by RECIST 1.1 criteria. [+25]

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