Health Trials

Advanced Triple Negative Breast Cancers

1

Review clinical trials related to Advanced Triple Negative Breast Cancers. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Selinexor & Talazoparib in Advanced Refractory Solid Tumors; Advanced/Metastatic Triple Negative Breast Cancer (START)

This is a single arm, open-label, phase I dose finding study, followed by a phase II expansion study. Phase I will be carried out in a modified 3+3 dose escalation design, with a projected enrolment of 33 patients with refractory solid tumors to determine the RP2D. In the phase II portion, a total of 30 patients with advanced/metastatic TNBC will be enrolled.

Participants needed: 63
Trial details
Phase: Phase 1, Phase 2Age: 18-99Biological sex: AllType: InterventionalSponsor: National University Hospital, SingaporeUpdated: Jul 25, 2025Locations: 1
Eligibility criteria

All patients must sign an informed consent in accordance with local institutiona... [+6]

Measurable disease by RECIST 1.1 criteria. [+25]

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