Age-related Cataract

3

Review clinical trials related to Age-related Cataract. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

The Impact of Surgical Procedures on Postoperative Outcomes in Cataract Phacoemulsification and Analysis of Related Factors

The goal of this observational study is to evaluate the location of phacoemulsification tip measured by intraoperative OCT during cataract surgeries and its impact on early postoperative changes of cornea and visual acuity. The main question it aims to answer is: In patients with age-related cataracts undergoing phacoemulsification, does the location (supracapsular, iris-lens diaphragm, or endocapsular) of the phaco tip affect postoperative corneal changes and visual acuity at early postoperative stage? Eyes having phacoemulsification for cataracts will receive intraoperative OCT imaging to evaluate the location of the phaco tip during surgery, and corneal changes and visual acuity will be measured postoperatively.

Participants needed: 300
Trial details
Age: 50-90Biological sex: AllType: ObservationalSponsor: Zhongshan Ophthalmic Center, Sun Yat-sen UniversityUpdated: Jun 3, 2026Locations: 1Duration: 1 Month
Eligibility criteria

Age ≥ 50 years and ≤ 90 years [+5]

Diagnosis of severe systemic disease (e.g., severe hypertension or Alzheimer's d... [+3]

Status: Not yet recruiting

Prednisolone Acetate Eye Drops for Pain Intervention in Second Eye Cataract Surgery

This study aims to evaluate the efficacy, safety, and potential mechanisms of prednisolone acetate eye drops for pain management in patients undergoing second-eye surgery for age-related cataracts. Researchers will compare prednisolone acetate eye drops to sodium hyaluronate eye drops to see if prednisolone acetate eye drops work to relieve intraoperative and postoperative pain during second-eye cataract surgery. Participants will: 1. Receive prednisolone acetate eye drops or sodium hyaluronate eye drop four drops within 2 hours before cataract surgery 2. Finish cataract surgery and routine postoperative follow-up 3. Pain questionnaire completed after cataract surgery

Participants needed: 70
Trial details
Phase: Phase 2Age: 50-80Biological sex: AllType: InterventionalSponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineUpdated: Sep 26, 2024
Eligibility criteria

Age between 50-80 years old; [+4]

History of ocular trauma, ocular surgery, uveitis, fundus disease, glaucoma, or... [+6]

Status: Recruiting

Comparison of Treatment With Preservative-free Dexamethasone 0.1% (Monofree Dexamethason) and Diclofenac 0.1% (Dicloabak) Eye Drops Versus Preserved Dexamethasone 0.1% (Maxidex) and Diclofenac 0.1% (Voltaren Ophtha) Eye Drops After Cataract Surgery

To compare treatment with preservative-free dexamethasone 0.1% (Monofree Dexamethason) and diclofenac 0.1% (Dicloabak) eye drops versus preserved dexamethasone 0.1% (Maxidex) and diclofenac 0.1% (Voltaren Ophtha) eye drops after cataract surgery in terms of postoperative inflammation, iatrogenic dry eye disease and cystoid macular edema.

Participants needed: 100
Trial details
Phase: Phase 4Age: 60+Biological sex: AllType: InterventionalSponsor: Universitaire Ziekenhuizen KU LeuvenUpdated: Jul 1, 2024Locations: 2
Eligibility criteria

Patients diagnosed with age-related cataract [+1]

Unwilling to sign informed consent [+11]