Aggressive Fibromatosis

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Review clinical trials related to Aggressive Fibromatosis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Nirogacestat in Premenopausal Females With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)

This study is being conducted to study how nirogacestat may affect the ovarian function of adult premenopausal women with progressing desmoid tumors/aggressive fibromatosis.

Participants needed: 50
Trial details
Phase: Phase 4Age: 18-40Biological sex: FemaleType: InterventionalSponsor: SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, GermanyUpdated: Jun 22, 2026Locations: 23
Eligibility criteria

Participant is female, postpubertal aged ≥18 and ≤40 years of age at the time of... [+4]

Participant has known malabsorption syndrome or preexisting gastrointestinal con... [+11]