Health Trials

AL Amyloidosis (AL)

2

Review clinical trials related to AL Amyloidosis (AL). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Sonrotoclax Plus Dexamethasone With or Without Daratumumab Regimen in Patients With t(11;14) Primary AL Amyloidosis

The goal of this study is to evaluate the efficacy and safety of Sonrotoclax combined Regimen in patients with t(11;14) AL amyloidosis. Participants will receive the Sonrotoclax Plus Dexamethasone regimen with or without Daratumumab for 12 cycles. The Hematologic Response, Organ Response, Survival, and Safety will be evaluated.

Participants needed: 39
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Peking University People's HospitalUpdated: Jan 13, 2026
Eligibility criteria

Patients who meet the diagnostic criteria for Primary Systemic Light Chain Amylo... [+15]

Meets the diagnostic criteria for active multiple myeloma or active lymphoplasma... [+22]

Read more
Status: Recruiting

Safety and Efficacy of Metabolically Armed BCMA CAR-T Cells (Meta10-BCMA) in the Treatment of r/r Plasma Cell Neoplasms Clinical Research

A Study of Metabolically Armed BCMA CAR-T Cells Therapy for Patients With Relapsed and/or Refractory Plasma Cell Neoplasms.

Participants needed: 36
Trial details
Phase: Early Phase 1Age: 19-75Biological sex: AllType: InterventionalSponsor: Anhui Provincial HospitalUpdated: Jul 25, 2025Locations: 1
Eligibility criteria

Age 19 to 75 years old, male or female. The subject or his/her guardian voluntar... [+18]

Any hematopoietic stem cell transplant(HSCT) within 2 months prior to the start... [+23]

Read more