Albumin; Double

1

Review clinical trials related to Albumin; Double. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

PREVENTION OF WORSENING RENAL FUNCTION OF INTRAVENUS ALBUMIN IN HEART FAILURE PATIENTS

Patients hospitalized for acute decompensation of CHF are usually complicated by worsening renal function (WRF) which leads to diuretic resistance and inadequate decongestion as well as poor prognosis. WRF has been attributed to a reflex renal vasoconstriction elicited by intravascular volume depletion during brisk diuresis. The investigators hypothesize that CHF patients with hepatic dysfunction are more prone to WRF due to poor albumin production. This sub-group of CHF patients may benefit more (increased diuretic efficacy and protected against worsening renal function) by the use of IV loop diuretics in combination with an intravascular volume expander such as IV Human Albumin.

Participants needed: 250
Trial details
Phase: Phase 3Age: 18-95Biological sex: AllType: InterventionalSponsor: Democritus University of ThraceUpdated: Oct 8, 2024Locations: 1
Eligibility criteria

age over 18 yrs [+4]

hemodynamic collapse (at least one of the following: systolic blood pressure (BP... [+5]